Gerontology & Geriatric Research

CORRELATING ADULT STEM CELL FUNCTION, COUNTS AND QUALITY WITH BIOLOGICAL AGE

4^th International Conference on Geriatrics & Gerontological Nursing

October 3-4, 2016 | London, UK

Kaushik Dilip Deb

DiponEd BioIntelligence, India

Posters & Accepted Abstracts: J Gerontol Geriat Res

Abstract:

Progressive decline in biochemical homeostatic and regenerative capacities, has been attributed to aging and age related disorders. However, the biological age of a person can be different from his chronological age. Degenerative changes in tissue-specific stem cells, stem cell niches can occur, along with age or due to life style conditions. In this study, we attempted to correlate various Blood and Adipose derived adult stem cells (eg; haematopeitic stem cells, VSELs, APSCs, MSCs etc.) function, counts and quality with people�??s Chronological and Biological age. Participants (n= 20) were chosen from various age groups (45 to 55 years) and (stressful/ relaxed) lifestyle backgrounds. A separate group of (n= 10) participants (with age between 45 to 55 years) were enrolled in our 21 days Mind and Body Anti Aging retreat (developed previously). The stem cell counts and function / quality was screened in both the groups, at the end of the retreat. The biological ages of all the participants were calculated following a standard scoring system. We observed a decline in HSC, VSELs, APSCs etc., stem cell counts and functional profile with age and stress. This correlated with the observed increase in the Biological age scoring of the participants. An increase in counts and functional profiles of stem cells was observed in participants who were enrolled in the Mind and Body Retreat program. This correlated well with the observed reduction in Biological age scoring in the participants. Regenerative potential is directly related to Stem cell function, counts and Biological age of a person.