Journal of Blood Disorders & Transfusion

Chemistry of dark red colored liquid tissue having deep metallic odour through oxygenated α, β-unsaturated aldehyde

6^th International Conference on Hematology

October 03-05, 2016 Orlando, USA

Dhrubo Jyoti Sen, Pankaj H Prajapati, Rajat Chaudhary, Heta Shah, Rutvi Patel, Dhruvi Pandit and Ravi Pandya

Gujarat Technological University, India

Posters & Accepted Abstracts: J Blood Disord Transfus

Abstract:

Blood is a liquid tissue having red in color with characteristic metallic smell or odour. Smells are notoriously hard to pin down, describe and identify but most people agree that the smell of fresh blood has a distinct, metallic tang. You might assume this comes from the iron in our blood, but an organic compound; a type of aldehyde is to blame. (2E)-3-(3-pentyl-2-oxiranyl) acryaldehyde or trans-4,5-Epoxy-(E)-2-decenal or (2E)-3-[(2S,3S)-3-pentyloxiran-2-yl]prop-2-enal all are same substances having aldehyde moiety (-CHO). Unsaturated fatty acid has tendency to undergo rancidification due to the presence of double bond (sigma bond (Ï?) and pi bond (Ï?)) in oxidative catabolism in vivo by oxidase enzyme and in vitro due to air oxidation. Unsaturated part undergoes reaction steps by Initiation, Propagation and Termination steps followed by free radical formation in Initiation step, peroxide formation in Propagation step and hydroperoxide step in Termination step which produce obnoxious smell due to the formation of epoxide. Since blood is a biological fluid tissue so it produces metallic smell of characteristic odour. Metallic odour of flesh or blood comes from the rancidification of linoleic acid is due to oxidation of unsaturated bonds by oxygen through initiation, propagation and termination steps of α, β-unsaturation of acid into oxygenated aldehyde. The unpleasant foul smell is generated by biochemical oxidative reactions both in vivo & in vitro. LogP of this substance is 1.73 so it is semi polar in nature due to three membered oxirane ring and double bond and aldehyde linkage, so it is easily atomized into the atmospheric environment to disperse the odour.

Biography :

Email: dhrubosen69@yahoo.com