Journal of Nanomedicine & Nanotechnology

Chemical analysis, antimicrobial and wound-healing evaluation of geophagic and cosmetic clays

8^th World Medical Nanotechnology Congress & Expo

June 08-09, 2016 Dallas, USA

Bisi-Johnson, Oyelade H A and Adewole OS

Obafemi Awolowo University, Nigeria

Posters & Accepted Abstracts: J Nanomed Nanotechnol

Abstract:

Naturally occurring geophagic and cosmetic clays are among potential nanomaterial commonly used in rural and urban areas of Nigeria for tradition and medicinal purposes. This study analyzed the chemical constituents and evaluated the potentials of the clays as antimicrobials and agents in wound management. Mined and markets clay samples obtained from Delta, Edo and Osun States (Southern Nigeria) were collected aseptically. Questionnaires were administered to obtain information on geophagia and cosmetic clay use. Samples were transported on ice to the laboratory for analysis. Organic and moisture content estimation, colour determination, cation exchange capacity (CEC), exchangeable cations, pH, total elemental composition, heavy metal analysis, radiation estimation were by standard methods. In-vivo antimicrobial and wound repair/regeneration experiments were also carried out. The pH values of the clays in water were 2.8 - 5.3 and in CaCl2 (2.7-5.1). The clay colour ranged from dark grey to white. The CEC values had a mean value of 19.20±0.01 meq/100 g. Lead values were above allowable limits of 0.06 ppm across all the samples. The radiation readings had highest value for γ at 2.64 x 10-8±0.04 mSv/hr. Eko black clay was active against all test bacteria and had the highest zone of inhibition (20 mm) against E. coli NCBI 86. In the in-vivo test, first clay treated subject completed healing by day 11 comparable to (Sufra tulle antibiotic) treated control Albino Wistar rat healing on day 7. The study concluded that geophagic and cosmetic clays could be useful in the management of wounds. However, the clays could also cause health issues due to heavy metal contamination. .

Biography :

Email: Mary Bisi-Johnson@cherishdoc