Journal of Bacteriology & Parasitology

Changes in lipid profiles of HIV positive adults over 9 months at a Harare HIV clinic: A longitudinal study

4^th International Congress on Bacteriology and Infectious Diseases

May 16-18, 2016 San Antonio, USA

Doreen Nehumba

University of Stellenbosch, South Africa

Posters & Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Human immunodeficiency virus (HIV) infection, together with antiretroviral drugs is often associated with changes in biochemical and metabolic parameters including changes in lipid profiles. The aim of the study was to compare the changes in lipid profiles among HIV positive outpatients who are on antiretroviral therapy (ART) and those who are ART-naive over a nine months period. 171 patients were investigated, 79% were ART-experienced, while 82% of those on treatment were on NVP/EFV first line ART. More than 60% of ART-naive and ART-experienced patients had some form of dyslipidemia either at baseline or at follow-up but the lipid median values for the two groups was within normal limits. At baseline, median levels of total cholesterol (TC) and high density lipoprotein (HDL) were slightly higher in the ART-experienced group. After nine months of antiretroviral treatment the average lipid values were still within normal limits. Interestingly, there was higher increase in HDL over time in the ART negative group compared to the ART positive group. There was a decrease in TC/HDL ratio in both groups over time. HIV positive patients frequently show various forms of dyslipidemia but there are no changes in average atherogenic lipid levels after nine months.

Biography :

Email: doreenmaranda@yahoo.co.uk