Journal of Pharmacogenomics & Pharmacoproteomics

Blood needs for anemic patients admitted at ICU can be evaluated by lactate level and vital parameters at admission time

5^th International Conference on Predictive, Preventive and Personalized Medicine & Molecular Diagnostics

December 01-02, 2016 Valencia, Spain

Lordian Nunci, Ilir Ohri and Edi Grabocka

Department of Anesthesiology & Intensiv Care
University Hospital Mother Tereza, Albania

Posters & Accepted Abstracts: J Pharmacogenomics Pharmacoproteomics

Abstract:

Introduction & Objective: Evaluation of red cell transfusion effects on tissue oxygenation by measuring blood lactate levels before and after hemotransfusion. Blood lactate level is suggested as sensitive parameter to evaluate tissue oxygenation. The aim of this study was to verify the efficiency of hemotransfusions that were performed on patients in intensive care based on lactate level. Material & Methods: In this prospective observational study on 59 patients who considered that red cell transfusion (the patients more that 25 point according to APACHE II-score were excluded). We monitor vital signs (BP, HR) at admission and also was strictly observed lactate level and hemoglobin level at admission before red cell transfusion (pre-T), two hours after transfusion (2 hours post-T) and 24 hours after (24 hours post-T with or no any another red cell transfusion). At first the patients group based at hemoglobin level, Group Ia with Hb <8 g/dl and Group IIb with Hb â?¥8 g/dl. After that the patients group again based at lactate level, Group Ic lactate level â?¥2.4 and Group IId lactate level <2.4. Results: Comparison between group Ia and group IIb as belongs hemoglobin level demonstrate significance only at admission pre-T and lost significance at 2 hours post-T and 24 hours post-T, at the other hand differences between group Ic and group IId as belongs hemoglobin level stay significant at pre-T, 2 hours post-T and 24 hours post-T. Conclusions: Statistical significant evaluation (p<0.05) between above mentioned groups shown that lactate level are very sensitive indicator in measuring of tissue oxygenation. Another important finding was significant high mortality and morbidity at patient group with lactate level â?¥2.5.

Biography :

Email: lordiannunci@yahoo.com