Journal of Food Processing & Technology

Are ghrelin levels lower in obese Emirati college students?

20^th International Conference on Nutrition, Food Science and Technology

April 16-17, 2018 Dubai, UAE

Dimitrios Papandreou, Christos Karavolias, Tasnim Medani, Eleana Kafeza and Antonios Zampelas

Zayed University, UAE
The Doctor′s Medical Center, UAE
Agricultural University of Athens, Greece

Posters & Accepted Abstracts: J Food Process Technol

Abstract:

Aim: Ghrelin is a 28-amino acid that is produced in the stomach. Strong evidence indicates the effects of ghrelin in its potential role in the pathogenesis of obesity, insulin resistance (IR) and type 2 diabetes. The aim of this study was to investigate the relationship of ghrelin levels with obesity, insulin resistance and glucose in normal and obese subjects. Methods: Twenty subjects (normal weight=13) and (Obese=7) aged 20-22 out of 250 students participated in the study. Fasting plasma ghrelin, insulin and glucose levels were measured after overnight fasting. Insulin resistance was also calculated by HOMA-IR. The study received approval from the ethical committees of �??Zayed University�?� and �??Doctors Medical Center�?� while all subjects signed a consent form. Body weight and height was collected for all subjects using SECA 600 model while obesity was defined as BMI>30 kg/m2, according to the criteria of international obesity task force plasma ghrelin, glucose, insulin and C-reactive protein (CRP) levels were measured in the morning after fasting overnight. Conclusions: Ghrelin levels are significantly lower in obese subjects. Moreover, Obesity (BMI) and Insulin resistance (HOMA)IR are significantly independently associated with ghrelin levels in obese college students. More studies are needed to elucidate the relationship of ghrelin with BMI and IR. References 1. Tschöp M, Weyer C, Tataranni PA, et al (2001) Circulating ghrelin levels are decreased in human obesity. Diabetes; 50: 707�??709. 2. Schöfl C, Horn R, Schill T, et al (2002) Circulating ghrelin levels in patients with polycystic ovary syndrome. J Clin Endocrinol Metab; 87: 4607�??4610. 3. Purnell JQ, Weigle DS, Breen P, et al (2003) Ghrelin levels correlate with insulin levels, insulin resistance, and high-density lipoprotein cholesterol, but not with gender, menopausal status, or cortisol levels in humans. J Clin Endocrinol Metab; 88: 5747�??5752. 4. Sato T, Ida T, Nakamura Y, et al (2014) Physiological roles of ghrelin on obesity. Obes Res Clin Pract; 8: e405-413

Biography :

Dimitrios Papandreou is an Associate Professor of Nutrition and Dietetics and the Assistant Dean for Research and Graduate studies at Zayed University, UAE. He has published more than 70 original publications since 2008. He is also a Registered Dietitian from USA.
Email:Dimitrios.Papandreou@zu.ac.ae