Muhammad Arshad Rafiq^1,2, Tamara T Koopmann¹, Laura A Zahavich³, Meena Fatah¹ and Robert M Hamilton^1*

¹Physiology and Experimental Medicine, The Hospital for Sick Children and Research Institute, Toronto, Ontario, M5G 0A4, Canada

²Department of Biosciences, COMSATS Institute of Information Technology (CIIT), Park Road, Tarlai Kalan, Islamabad, 45550, Pakistan

³The Hospital for Sick Children,, Cardiology and Clinical Genetics, The Hospital for Sick Children and Research Institute, Toronto, Ontario, M5G 0A4, Canada

^*Corresponding Author: