1Centre for Evaluation and Information on Drug-Addictovigilance, Clinical Pharmacology, Hôtel Dieu, Institute of Biology, 9 Quai Moncousu, 44093, Nantes Cedex 1, France
2EA 4275 Biostatistics, Pharmacoepidemiology and Subjective Health Measures, Faculty of Pharmaceutical and Biological Sciences, Nantes, France
3Biometrics Platform, Promoting Clinical Research Unit, CHU Nantes, France
4Regional Department of Health Insurance Medical Service of the Loire, Nantes, France