Safeguarding Stem Cell-Based Regenerative Therapy against Iatrogenic Cancerogenesis: Transgenic Expression of DNASE1, DNASE1L3, DNASE2,DFFB Controlled By POLA1 Promoter in Proliferating and Directed Differentiation Resisting Human Autologous Pluripotent Induced Stem Cells Leads to their Death

Marek Malecki^1,2*, Christine LaVanne², Dominique Alhambra², Chaitanya Dodivenaka³, Sarah Nagel³ and Raf Malecki^1,4

¹Phoenix Biomolecular Engineering Foundation, San Francisco, CA 94105, USA, E-mail: mm@pbmef.org

²University of Wisconsin, Madison, WI 53706, USA, E-mail: mm@pbmef.org

³South Dakota State University, Brookings, SD 57007, USA, E-mail: mm@pbmef.org

⁴San Francisco State University, San Francisco, CA 94123, USA, E-mail: mm@pbmef.org