Polytherapy with Reserpine and Glucagon-like Peptide-1 (GLP-1) Improves the Symptoms in Streptozotocin-Induced Type-1 Diabetic Mice by Reducing Inflammation and Inducting Beta Cell Regeneration

Evgenii Germanovich Skurikhin¹, Olga Victorovna Pershina^1*, Natalia Nikolaevna Ermakova¹, Lubov Alexandrovna Ermolaeva¹, Vyacheslav Andreevich Krupin¹, Angelina Vladimirovna Pakhomova¹, Edgar Sergeevich Pan¹, Marie-Theres Zeuner², Darius Widera², Ekaterina Sergeevna Khmelevskaya¹, Vladimir Petrovich Fisenko³ and Alexander Mikhaylovich Dygai¹

¹Laboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Tomsk, Russia

²Stem Cell Biology and Regenerative Medicine Group, Department of Pharmacology, School of Pharmacy, University of Reading, Reading, United Kingdom

³Department of Pharmacology, Sechenov First State Medical University, Russia

^*Corresponding Author: