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MEFA (multiepitope fusion antigen)-Novel Technology for Structural Vaccinology, Proof from Computational and Empirical Immunogenicity Characterization of an Enterotoxigenic Escherichia coli (ETEC) Adhesin MEFA

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Research Article - (2016) Volume 7, Issue 3

Pilin Vaccination Stimulates Weak Antibody Responses and Provides No Protection in a C57Bl/6 Murine Model of Acute Clostridium difficile Infection

Grace A Maldarelli1, Hanover Matz1, Si Gao2, Kevin Chen2, Therwa Hamza2, Harris G Yfantis3, Hanping Feng2 and Michael S Donnenberg1*
1Department of Medicine, Division of Infectious Disease, University of Maryland School of Medicine, Baltimore, Maryland, USA, E-mail: mdonnenb@umaryland.edu
2Department of Microbial Pathogenesis, University of Maryland Dental School, Baltimore, Maryland, USA, E-mail: mdonnenb@umaryland.edu
3Department of Pathology and Laboratory Medicine, VAMHCS, University of Maryland School of Medicine, Baltimore, Maryland, USA, E-mail: mdonnenb@umaryland.edu
*Corresponding Author: