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Journal of Nanomedicine & Nanotechnology

Mini Review - (2023) Volume 14, Issue 3

Nanomedicine: Advantages and Disadvantages of Nanomedicine
Dr. Shiya Soliman*
 
Department of Nanomedicine, University of Landmark Nanotechnology, Nigeria
 
*Correspondence: Dr. Shiya Soliman, Department of Nanomedicine, University of Landmark Nanotechnology, Nigeria, Email:

Received: 02-Mar-2023, Manuscript No. jnmnt-23-20218; Editor assigned: 06-Mar-2023, Pre QC No. jnmnt-23-20218; Reviewed: 22-Mar-2023, QC No. jnmnt-23-20218; Revised: 25-Mar-2023, Manuscript No. jnmnt-23-20218; Published: 31-Mar-2023, DOI: 10.35248/2157-7439.23.14.666.

Abstract

Nanomedicine is a quickly developing field of medication that utilizes nanotechnology to analyse, treat, and forestall different infections. It involves creating medical devices, therapies, and diagnostic tools that are safer, more efficient, and effective than traditional methods by utilizing nanoscale materials like nanoparticles. Nanomedicine has the potential to transform healthcare and enhance the lives of millions of people all over the world. The use of nanotechnology in medicine with the intention of enhancing disease diagnosis, treatment, and prevention is referred to as nanomedicine. Nanoscale materials, systems, and devices for medical applications are the subject of this research. Nanomedicine is a rapidly expanding field that has the potential to transform healthcare. The size of nanoparticles ranges from one to one hundred nanometers. They can be designed to have particular chemical and physical properties, like size, shape, and surface charge, which can make them suitable for use in medical procedures. For instance, iron oxide nanoparticles can be utilized as a contrast agent for magnetic resonance imaging (MRI) while gold nanoparticles can be used as contrast agents in imaging studies.

Keywords

Nanomedicine; Nanotechnology; Nanoscale Materials; Nanometers; Nanoparticles; Therapies and Healthcare; Magnetic Resonance Imaging (MRI)

INTRODUCTION

The emerging field of medicine known as nanomedicine places an emphasis on the application of nanotechnology to the diagnosis, treatment, and prevention of diseases. This technology has the potential to change the way we think about medicine because it gives us new tools and methods that could make treatments better and more tailored to each patient. However, as with any new technology, nanomedicine has both benefits and drawbacks [1].

The ability to deliver drugs directly to the site of the disease, thereby lowering the risk of adverse effects and increasing efficacy, is one of the main advantages of nanomedicine. Nanoparticles can be intended to target explicit cells or tissues, like malignant growth cells, and delivery the medication just when they arrive at the objective site. One of the main benefits of nanomedicine is that it can target specific body cells or tissues, making treatment more precise and effective. This is due to the fact that nanoscale materials and devices are able to interact with biological systems on a molecular and cellular level, enabling them to be tailored to particular biological targets. For instance, nanoscale drug delivery systems can be made to specifically target cancer cells, reducing side effects and increasing treatment efficacy. Nanomedicine's ability to get around biological barriers like the blood-brain barrier, which can prevent drugs from reaching their intended targets, is another advantage. Drugs can more easily reach their targets if nanoparticles and other nanoscale materials are designed to bypass these barriers. Additionally, disease diagnosis could be made quicker and more precisely with nanomedicine. Nanoscale sensors and imaging advancements can distinguish biomarkers and different signs of sickness at exceptionally low fixations, considering prior discovery and therapy. Patients could benefit from improved outcomes and lower healthcare costs as a result [2].

Nanomedicine has the potential to address many of the issues that the healthcare industry currently faces, in addition to its potential medical benefits. By tailoring treatments to each patient's specific requirements, for instance, it might make it possible to provide care that is more individualized and patient-centered. By enabling the development of new drugs and drug delivery systems that are more effective than this targeted approach, it could also assist in addressing the issue of drug resistance by minimizing damage to healthy cells and tissues and lowering the drug's overall toxicity [3]. Nanoparticles can likewise be utilized to make clinical gadgets that are more viable and more secure than conventional gadgets. For instance, biomarkers of disease can be detected in blood or other bodily fluids with the help of nanosensors, allowing for earlier diagnosis and treatment. At the cellular level, nanorobots can deliver drugs or perform surgical procedures, which can be especially helpful in treating diseases that are difficult to access with conventional surgical methods. Regenerative medicine, in which nanoscale materials can be used to stimulate tissue regeneration and repair, is another potential application of nanomedicine. Nanofibers can be used to construct scaffolds for tissue engineering, while nanoparticles can be used to deliver growth factors or other molecules that encourage tissue repair.

Nanomedicine has many potential advantages, but it also has some risks and difficulties. Nanoparticle toxicity, which can vary depending on their size, shape, and surface properties, is one cause for concern. The difficulty of manufacturing nanoparticles on a large scale and ensuring their safety and effectiveness is another obstacle [4].

ADVANTAGES OF NANOMEDICINE

Precision medicine: One of the biggest advantages of nanomedicine is its ability to deliver drugs and other therapeutic agents directly to the site of the disease. This precision medicine approach reduces the risk of side effects and maximizes the therapeutic effect of the drug.

Early diagnosis: Nanotechnology-based imaging techniques, such as magnetic resonance imaging (MRI) and computed tomography (CT) scans, allow for earlier and more accurate diagnosis of diseases, such as cancer.

Targeted therapy: Nanoparticles can be engineered to target specific cells or tissues in the body, which is particularly useful in cancer therapy. This targeted therapy approach reduces the risk of damage to healthy cells and tissues [5].

Improved drug delivery: Nanoparticles can be used to improve drug delivery, by increasing the drug’s solubility, bioavailability, and stability. This allows for lower doses of drugs to be used, reducing the risk of toxicity and side effects [6].

Regenerative medicine: Nanoparticles can be used to deliver growth factors and other regenerative agents to damaged tissues, promoting tissue repair and regeneration.

Disadvantages of nanomedicine

Toxicity: The use of nanoparticles in medicine is still a relatively new field, and there is limited knowledge on their long-term toxicity. Studies have shown that some nanoparticles can accumulate in the body and cause damage to organs and tissues [7].

Cost: The development and production of nanoparticles can be expensive, which could limit their availability and affordability.

Regulatory challenges: The use of nanomedicine in humans is subject to strict regulatory approval, which can slow down the development and implementation of new therapies [8].

Ethical concerns: There are also ethical concerns surrounding the use of nanomedicine, particularly in areas such as genetic engineering and enhancement [9].

Limited knowledge: There is still a lot to learn about the interactions between nanoparticles and the human body. More research is needed to fully understand the potential benefits and risks of nanomedicine [10].

CONCLUSION

The field of nanomedicine continues to advance rapidly in spite of these obstacles, with brand-new discoveries and advancements constantly being made. The potential benefits of nanomedicine are likely to increase, paving the way for new and more effective treatments for a wide range of diseases as researchers continue to develop and refine nanoscale medical materials and devices. In terms of disease diagnosis, treatment, and prevention, nanomedicine offers numerous advantages. However, it also has some drawbacks, such as toxicity, price, and difficulties with regulation, ethical questions, and a lack of knowledge. Nanomedicine has the potential to revolutionize medicine and improve patient outcomes despite these obstacles. In order to fully realize this field's potential, ongoing research and development are essential.

REFERENCES

  1. Kermanizadeh A, Vranic S, Boland S, Moreau K, Baeza-Squiban A, et al. An in vitro assessment of panel of engineered nanomaterials using a human renal cell line: cytotoxicity, pro-inflammatory response, oxidative stress and genotoxicity. BMC Nephrol. 2013; 14:96.
  2. Indexed at, Google Scholar, Crossref

  3. Chen R, Qiao J, Bai R, Zhao Y, Chen C. Intelligent testing strategy and analytical techniques for the safety assessment of nanomaterials. Anal Bioanal Chem. 2018; 410(24): 6051-6066.
  4. Indexed at, Google Scholar, Crossref

  5. Giannakou C, Park MV, Jong WHD, Loveren HV, Vandebriel RJ, et al. A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements. Int J Nanomedicine. 2016; 11:2935-52.
  6. Indexed at, Google Scholar, Crossref

  7. Melaku W, Solomon G. Prevalence of intestinal protozoa and soil transmitted helminths infections among school children in Jaragedo Town, South Gondar zone of Ethiopia. J Trop Med. 2022;5747978.
  8. Crossref, Google Scholar

  9. Khan W, Rahman H, Rafiq N, Kabir M, Ahmed MS, Escalante PD. Risk factors associated with intestinal pathogenic parasites in schoolchildren. Saudi J Biol Sci. 2022;29(4):2782-2786.
  10. Indexed at, Google Scholar, Crossref

  11. Hemphill A, Müller N, Müller J. Comparative pathobiology of the intestinal protozoan parasites Giardia lamblia, Entamoeba histolytica, and Cryptosporidium parvum. Pathogens. 2019;8(3):116.
  12. Indexed at, Google Scholar, Crossref

  13. Opara KN, Udoidung NI, Opara DC, Okon OE, Edosomwan EU, Udoh AJ, et al. The impact of intestinal parasitic infections on the nutritional status of rural and urban school-aged children in Nigeria. Int J MCH AIDS. 2012;1(1):73.
  14. Indexed at, Google Scholar, Crossref

  15. Elespuru R, Pfuhler S, Aardema MJ, Chen T, Doak SH, et al. Genotoxicity Assessment of Nanomaterials: Recommendations on Best Practices, Assays, and Methods. Toxicol Sci. 2018; 164(2):391-416.
  16. Indexed at, Google Scholar, Crossref

  17. Pfuhler S, Elespuru R, Aardema MJ, Doak SH, Maria Donner E, et al. Genotoxicity of nanomaterials: refining strategies and tests for hazard identification. Environ Mol Mutagen. 2013; 54(4):229-239.
  18. Indexed at, Google Scholar, Crossref

  19. Levecke B, Montresor A, Albonico M, Ame SM, Behnke JM, Bethony JM, et al. Assessment of anthelmintic efficacy of mebendazole in school children in six countries where soil-transmitted helminths are endemic. PLoS Negl Trop Dis. 2014;8(10):e3204.
  20. Indexed at, Google Scholar, Crossref

Citation: Soliman S (2023) Nanomedicine: Advantages and Disadvantages of Nanomedicine. J Nanomed Nanotech. 14: 666.