Journal of Psychiatry

Multifocal Motor Neuropathy Case Report

Gabriel Alejandro B. Baroque University of Santo Tomas Hospital, Philippines

Published: 16-Sep-2020

Abstract

We report a case of a 51-year old Filipino female with multifocal motor neuropathy who presented with chronic weakness of the left foot which without any sensory deficits. With the history chronic progressive weakness, lack of sensory deficits, confirmatory by biochemical workups and diagnostics: an elevated ganglioside GM1 antibody test which revealed a titer of 1:12800, electromyography and nerve conduction confirmed the diagnosis of multifocal motor neuropathy. Treatment of intravenous immunoglobulin with a dose of 2g/kg over 2-5 days was initiated and repeated every 2 months with noticeable improvement.Multifocal motor neuropathy is a rare disorder which has a prevalence of 0.6 per 100,000 individuals. It is seen in more in males with a ratio of 2.7:1. It is described as a pure motor disease without sensory deficits which is predominantly seen in the upper extremities.7 The diagnosis for the disorder is supported by determination of ganglioside GM1 antibodies, electromyography and nerve conduction velocity study (EMG-NCV).

Biography:

Gabriel Alejandro B. Baroque has completed his MD at the age of 28 from the University of Santo Tomas in Manila, Philippines. He is currently a Neurology resident in the same institution. He has been guided by Dr. Alejandro C. Baroque II and Dr. Imelda S. David, both esteemed professors and practicing in the fields of Neurology and Psychiatry.

Speaker Publications:

1. Chad DA, Hammer K, Sargent J. “Slow resolution of multifocal weakness and fasciculation: a reversible motor neuron syndrome”. Neurology. 1986 Sep 1; 36(9):1260.

2. Feldman EL, Bromberg MB, Albers JW, Pestronk “A. Immunosuppressive treatment in multifocal motor neuropathy”. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society.1991 Sep; 30(3):397–401.

3. Olney RK, Lewis RA, Putnam TD, Campellone Jr JV. “Consensus criteria for the diagnosis of multifocal motor neuropathy”. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine. 2003 Jan; 27(1):117–21.

4. Van Asseldonk JT, Franssen H, Van den Berg-Vos RM, Wokke JH, Van den Berg LH. “Multifocal motor neuropathy”. The Lancet Neurology. 2005 May 1; 4(5):309–19.

5. Joint Task Force of the EFNS and the PNS. “European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of multifocal motor neuropathy”. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society–first revision. Journal of the Peripheral Nervous System. 2010 Dec; 15(4):295–301.

10th International Conference on Neurological disorders & Stroke; Webinar-August 21-22, 2020.

Abstract Citation:

Gabriel Alejandro B. Baroque, Multifocal Motor Neuropathy: A Case Report, Stroke Congress 2020, 10th International Conference on Neurological disorders & Stroke Webinar- August 21-22, 2020.

(https://stroke.neurologyconference.com/abstract/2020/multifocal-motor-neuropathy-a-case-report)