Mice Deficient in Rap1A GTPase Display Reduced Adhesion of Hematopoietic and Mesenchymal Stromal Cells but Intact Hematopoietic Repopulation Potential

Erika Fleck¹, Stephan Göttig¹, Harald Kropshofer², Juliane Steinmann³, Annette Dorn³, Brigitte Rüster¹, Erhard Seifried¹, Jürgen Scheele³ and Reinhard Henschler^1,4*

¹Institute for Transfusion Medicine and Immune Hematology, German Red Cross Blood Service, Medical Center of the Johann Wolfgang Goethe University, Frankfurt (Main), Germany

²F Hoffmann-La Roche Ltd, Pharmaceuticals Division, Product Development, Basel, Switzerland

³Department of Hematology and Oncology, University Hospital Medical Center, Freiburg, Germany

⁴Blood Centers Zürich and Chur, Swiss Red Cross Blood Service, Zürich and Chur, Switzerland

^*Corresponding Author: