Fibrinogen Maracaibo: Hypo-Dysfibrinogenemia Caused by a Heterozygous Mutation in the Gen that Encodes for the Fibrinogen Aα Chain (G.1194G>A: P.Gly13>Glu) with Diminished Thrombin Generation

Marchi R^1*, Rojas H², Echenagucia M³, Meyer M⁴, Acosta M⁵, Apitz R³ and Ruiz-Sáez A³

¹Centro de Medicina Experimental, IVIC, Caracas, República Bolivariana de, Venezuela

²Instituto de Inmunología, Universidad Central de Venezuela, República Bolivariana de, Venezuela

³CNH-Banco Municipal de Sangre, DC, República Bolivariana de, Venezuela

⁴Department of Medical Engineering and Biotechnology, University of Applied Sciences, Jena, Germany

⁵Banco de Sangre del Estado Zulia, República Bolivariana de, Venezuela