Efficiency of Exosome Production Correlates Inversely with the Developmental Maturity of MSC Donor

Tian Sheng Chen; Ronne Wee Yeh Yeo; Fatih Arslan; Yijun Yin; Soon Sim Tan; Ruenn Chai Lai; Andre Choo; Jayanthi Padmanabhan; Chuen Neng Lee; Dominique PV de Kleijn; Kok Hian Tan; Sai Kiang Lim

doi:10.4172/2157-7633.1000145

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Research Article - (2013) Volume 3, Issue 3

Efficiency of Exosome Production Correlates Inversely with the Developmental Maturity of MSC Donor

Tian Sheng Chen^1,⁸^*, Ronne Wee Yeh Yeo^1,², Fatih Arslan³, Yijun Yin¹, Soon Sim Tan¹, Ruenn Chai Lai¹, Andre Choo⁴, Jayanthi Padmanabhan⁴, Chuen Neng Lee⁵, Dominique PV De Kleijn^3,⁶, Kok Hian Tan⁷ and Sai Kiang Lim^1,⁵^*: ¹Institute of Medical Biology, A*STAR, 8A Biomedical Grove, 138648, Singapore, E-mail: RonneWeeYehYeo@gmail.com; ²National University of Singapore, Graduate School for Integrative Sciences and Engineering, 28 Medical Drive, 117456, Singapore, E-mail: RonneWeeYehYeo@gmail.com; ³Laboratory of Experimental Cardiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands, E-mail: RonneWeeYehYeo@gmail.com; ⁴Bioprocessing Technology Institute, A*STAR, 20 Biopolis Way, 138671, Singapore, E-mail: RonneWeeYehYeo@gmail.com; ⁵Department of Surgery, YLL School of Medicine, NUS, 5 Lower Kent Ridge Road, 119074, Singapore, E-mail: RonneWeeYehYeo@gmail.com; ⁶Interuniversity Cardiology Institute of the Netherlands, Catharijnesingel 52, 3511 GC Utrecht, The Netherlands, E-mail: RonneWeeYehYeo@gmail.com; ⁷Department of Maternal Fetal Medicine, KK Women’s and Children’s Hospital, 100 Bukit Timah Road, 229899, Singapore, E-mail: RonneWeeYehYeo@gmail.com; ⁸Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Key Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, College of Fisheries, Huazhong Agricultural University, Wuhan, Hubei, 430070, People’s Republic of China, E-mail: RonneWeeYehYeo@gmail.com

^*Corresponding Author(s):