Bruton's Tyrosine Kinase: Structure and Functions, Expression and Mutations

Ying Liu^1*, Guang-biao Zhou², Bo Zhang³ and Yong-qiang Liu²

¹The Shenzhen Key Lab of Gene and Antibody Therapy, Center for Biotech & BioMedicine and Division of Life Sciences, Graduate School at Shenzhen, Tsinghua University, China, E-mail: gbzhou@ioz.ac.cn

²Division of Molecular Carcinogenesis and Targeted Therapy for Cancer, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, China, E-mail: gbzhou@ioz.ac.cn

³National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, China, E-mail: gbzhou@ioz.ac.cn