Journal of Pharmacogenomics & Pharmacoproteomics

Shi-Fang Yan

Shi-Fang Yan
Associate Professor, Department of Medicine and Pharmacology, NYU School of Medicine
USA

Biography

Shi-Fang Yan has completed post doctoral training from Physicians and Surgeons College of Columbia University. She is an Associate Professor at the Department of Medicine and Pharmacology, New York University, School of Medicine. She is a leading investigator of the molecular and cellular mechanisms of diabetic complications, including ischemic disorders and vascular disorders. Her major focuses are on the dissection of the interplay between the three key molecules linked to vascular stress, including Egr-1, PKC, and RAGE. She has published more than 100 research/review articles in medical journals, including Nature Medicine, Journal of Clinical Investigation, PNAS, Circulation Research, FASEB, JBC, Atherosclerosis and etc. She was the Winners of the Council 2000 Cournand and Comroe Young Investigator Award and a best poster award (2005) at the American Heart Association. She has been serving as an Editorial Board Member, a grant reviewer at American Heart Association Cardiac Bio BCT 1 study section.

Research Interest

Her research interests are on the molecular and cellular mechanisms of diabetic complications, including ischemic disorders and vascular disorders. Following my initial findings of Egr-1 as a central mediator of stress responses in hypoxia and ischemia. Her major focuses are on the dissection of the contribution of the interplay between the three key molecules, Egr-1, PKCβ and RAGE, that exacerbates inflammation and damage, to heart disease-related vascular injury, such as atherosclerosis and limb ischemia, especially in diabetes.