Journal of Biomolecular Research & Therapeutics

Sarath Chandra Janga

Sarath Chandra Janga
Executive Editor
Institute for Genomic Biology
University of Illinois, USA

Biography

Dr. Sarath Chandra Janga obtained his Bachelors and Masters degrees in Bio-chemical Engineering and Biotechnology from the Indian Institute of Technology, Delhi. Following which he moved to Mexico to work as a Research associate at the Center for Genomic Sciences, National Autonomous University of Mexico (UNAM) from 2003 to 2007. Subsequent to which he obtained a PhD in Molecular and Systems Biology from the prestigious MRC Laboratory of Molecular Biology & Darwin college, University of Cambridge, UK from 2008-2010. After finishing his doctoral work in a short span of two and half years on employing computational and graph-theoretical approaches to studying problems in molecular and cellular biology, Sarath recently moved to states as an Independent research fellow at the Institute of Genomic Biology, University of Illinois at Urbana-Champaign working on the development of novel data mining and computational approaches for identifying drug molecules and in elucidating the design principles governing biological systems. Much before starting his PhD, Sarath worked extensively and co-ordinated a number of research projects, on transcriptional regulation, genome organization and comparative genomics in bacteria, at UNAM in Mexico. He has published more than 40 research papers, most of which are highly cited with a H-index of 15, on various aspects of prokaryotic and eukaryotic biology in the fields of computational molecular and systems biology.
Early in his career, he has been the founding member and vice chair of the student body of the International Society for Computational Biology (ISCB). He has been invited for more than 60 international seminars, talks and lectures in a number of countries for his pioneering work in understanding gene regulatory networks using computational and systems approaches. He has been invited as a reviewer for more than 30 international journals and has been on the editorial board of Network Biology, Asian pacific journal of Tropical Biomedicine and guest associate editor of Frontiers in Systems Biology.
 

Research Interest

Understanding gene regulatory mechanisms in eukaryotic organisms.
Evolution, prediction and organization of operons and regulons in prokaryotes.
Understanding regulatory networks and their topological properties in prokaryotes and eukaryotes.
Using computational approaches to infer functional relationships between gene products to improve annotation strategies.
 Integrating diverse kinds of biological interaction datasets like genome-wide associations, protein-protein, regulatory and signal transduction pathways to understand dynamic and systems level aspects of regulation and their implications for disease.
Mining genomes for novel antibiotic producing pathways and to understand mechanisms of drug resistance.
 Applying network-based approaches in understanding disease biology, drug discovery and in personalized medicine settings.