Hereditary Genetics: Current Research

Sahdeo Prasad

Sahdeo Prasad
Post-Doctoral Fellow, Department of Experimental Therapeutics
The University of Texas MD Anderson Cancer Center, USA

Biography

Dr. Sahdeo Prasad obtained his Ph.D. (Biotechnology), CSJM University, Kanpur, India and Indian Institute of Toxicology Research (CSIR), Lucknow, India. During doctoral research program, he extensively worked on signal transduction pathways in both in vivo and in vitro tumor models. Before joining his PhD program, Dr. Prasad received National Eligibility Test (CSIR - UGC-NET), Graduate Aptitude Test in Engineering (GATE) and Indian Council of Medical Research Junior Research Fellowship award (ICMR-JRF) by Govt. of India. After PhD, he joined as Post - Doctoral Fellow in Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, USA. His expertise is in the area of molecular biology with particular reference to molecular mechanisms of signal transduction in tumor cells. Dr. Prasad has discovered a number of phytochemicals with chemo-preventive effects against a variety of cancers and their mechanism of action. The current research focuses of Dr. Prasad are on investigating the effects of chemo-preventive and chemotherapeutic agents among natural products that could suppress the activation of pro-inflammatory transcription factors NF-kB and STAT3. Besides these, Dr. Prasad’s work is also focused on the effect of natural compounds on death receptor pathways, bone loss and chemosensitization of tumor cells. He has over 80 National and International publications, abstracts Indexed in 10 International conferences. He is also an editorial board member of various reputed journals.

Research Interest

Study of transcription factors NF-kappaB and STAT3 signaling pathway, death receptor pathway, extrinsic and intrinsic pathway of apoptosis, anticancer properties of natural compounds in both in vitro and nude mouse models, study of cell cycle by flow cytometry, study of oxidative stress in animal models, antioxidants, study of genotoxicity by chromosomal aberration and micronuclei assay, study of gene expression by using western blotting and RT-PCR, DNA binding assay by EMSA, reporter gene expression, Immunohistochemical analysis, studies on both in vivo and in vitro experimental models.