Gerontology & Geriatric Research

Johannes Grillari

Johannes Grillari, PhD
Associate Professor, Department of Biotechnology
University of Natural Resources, Austria

Biography

Johannes Grillari’s research focus is on improving our understanding of the molecular and physiological changes that occur during cellular aging and their impact on aging of organisms. In addition, he is interested in engineering of mammalian cells to improved model systems and cell factories.Johannes Grillari has graduated in Biotechnology at the University of Natural Resources and Life Sciences Vienna (BOKU) in Austria, where he also accomplished his PhD in the field of cell aging in 1999. Since then he has founded and is leading the Aging and Immortalization Research group at the Department of Biotechnology at BOKU. He has worked as visiting scientist in the lab of Angus Lamond in Dundee, Scotland, for half a year in the field of RNA biology. In 2010 he was appointed Associate Professor, in 2011 he co-founded Evercyte, a company generating and providing immortalized cells for biopharmaceutical research and development. He has published more than 51 peer reviewed papers, holds 6 patents and has been invited speaker to more than 30 international conferences.

Research Interest

Cellular aging
Replicative senescence
RNA biology
pre-mRNA splicing
non-coding RNA miRNA
Vesicle secretion
DNA damage and repair
Ubiquitin-proteasome system
Biotechnology
Recombinant protein production Chinese hamster ovary cells (CHO)