Journal of Vaccines & Vaccination

4^th International Conference on Vaccines & Vaccination

September 24-26, 2014 Valencia Convention Centre, Spain

Scientific Tracks Abstracts

• Inter-bilayer cross-linked multi-lamellar vesicles (ICMVs) for efficient co-delivery of antigen and adjuvant payloads

  Alan R Shaw, Adrienne Li, Darrell Irvine, Jackson Eby and Peter Demuth

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• Adjuvant-guidance of T cell responses

  Magdalena Tary-Lehmann

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• Antibody targeting of human T cell CD27 identifies genes and pathways related to inflammation

  Venky Ramakrishna

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• Evaluation of ZOSTAVAX? via the intradermal route using the MicronJet?

  Brian K Meyer, Chan Beals, Yotam Levin and Robert K Evans

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• Universal influenza vaccines: Prevention of infection against matched and mismatched strains

  Harry Kleanthous, Timothy Alefantis, Stephen Anderson, Thorsten Vogel, Orey J Crevar, Donald M Carter, Ray Oomen, Mark Parrington and Ted M Ross

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• DNA vaccines which encode natural adjuvants are more effective than canonical DNA vaccines

  Eric James Gowans

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• Immune memory resilience, a new way of evaluating adjuvants

  Jean-Pierre Y Scheerlinck

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• Novel lipid based adjuvants and delivery systems or induction of CD8 T cell immunity

  Lakshmi Krishnan

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• Establishment of lipid-based immunogens for the development of novel subunit vaccines

  Chih-Hsiang Leng

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• Highly immunogenic C-terminal binding domain of Clostridium difficile toxin A stimulates dendritic cell maturation

  Pele Choi-Sing Chong, Huang J H, Shen Z Q, Chen Y Z, Lien S P, Hsiao K N and Chang C C

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• The Cronobacter sakazakii ESP2949-1 phage induces dendritic cell maturation via activation of nuclear factor-κB and IL-12p40 in murine bone marrow

  Hyo-Ihl Chang and Tae-Woo An

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• Nasal administration of antigens using maltodextrin nanoparticles: A mechanistic study

  Didier Betbeder

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• Stabilized liposomes carrying bee venom new formulation is the breakthrough of pain and anaphylaxis and death in mice under venom immunotherapy

  Maria Helena Bueno da Costa

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• Live vaccine for equine influenza on the base of cold-adapted recombinant strain A/HK/Otar/6:2/2010

  Sandybayev Nurlan

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• Polio outbreak in the Middle East: Update

  Randa Hamadeh

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• Outer membrane vesicle of bacteria: Friend or foe?

  Seyed Davar Siadat

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• Adjuvant properties of outer-membrane-vesicle in hepatitis B surface based vaccine

  Arfa Moshiri

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• Role of interferon gamma as immune adjuvant in Labeo rohita

  Megha Kadam Bedekar, Praveena K Soman, Makesh M, Gayatri Tripathi and K V Rajendran

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• Finding a safe, efficacious and stable vaccine in the ricin protein fold

  Leonard A Smith

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• A phase 1 clinical trial of Hantaan virus and Puumala virus M-segment DNA vaccines for hemorrhagic fever with renal syndrome delivered by intramuscular electroporation

  Connie S Schmaljohn

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• MVA-BN? (IMVANEX?/IMVAMUNE?): A non-replicating, new generation smallpox vaccine available for updating smallpox preparedness plans

  Nathaly Arndtz-Wiedemann

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• A vaccine pipeline: Using phage display for identification of immunogenic proteins and generation of human antibodies for diagnostics and therapy

  Michael Hust

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• Quality and consistency of cell culture media with a highlight on FMDV

  Serge Ohreser

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• Vaccine development at animal biosafety level four: Standards and challenges

  Jean L Patterson

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• Low dose antigen exposure in extreme early life promotes adaptive immune response in lambs and piglets

  Heather L Wilson, J Alex Pasternak, Siew Hon Ng, Rachelle M Buchanan, Sonja Mertins and Volker Gerdts

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• Study immune correlates of vaccine-induced protective immunity against rotavirus infection and diarrhea using B cell deficient neonatal gnotobiotic pigs

  Lijuan Yuan, Ke Wen, Tammy Bui, Mariah Weiss, Guohua Li, Jacob Kocher, Xingdong Yang, Sherrie Clark-Deener and David Ayares

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• Targeting aminopeptidase N on enterocytes rapidly induces an IgA response in a pig model

  Eric Cox

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• Use of ORF-1 product Rep in prevention and diagnosis of porcine circovirosis

  Silvia Pellicer

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• Properties of ghost bacterial cells obtained by hybrid material with silver nanoparticles (PVA/AgNps) as well as their opportunities for use in vaccine prophylactics

  Daniela Pencheva

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• Impact of three inactivated bovine viral diarrhoea (BVD) vaccines on bulk milk p80 (NS3) ELISA readings in commercial Irish dairy herds

  Riona Sayers

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• Construction of Phix174 gene E mediated lysis system for generation of Salmonella Enteritidis ghost, and its evaluation as a vaccine candidate for the immunogenicity and protective efficacy against avian salmonellosis

  Chetan V Jawale and John Hwa Lee

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• Use of viral interference against avian influenza and establishment of protection levels in field outbreaks in Mexico

  Inkar Castellanos

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• Mimogen-a new strategy for post-exposure vaccine development

  Yuzhang Wu

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• Generation of robust immunity following DNA vaccine immunization enhanced by intradermal electroporation

  Kate E Broderick, Amir S Khan and Niranjan Y Sardesai

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• M2SR: A robust flu vaccine with long-lasting, cross-protective immunity

  Pamuk Bilsel

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• In vivo electroporation for improvement of therapeutic DNA vaccine against chronic hepatitis B infection

  Lucyna Cova

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• A synthetic multi-antigen approach targeting Plasmodium falciparum malaria

  Ferraro B, Espinosa D A, Balakrishnan A, Reuschel E L, Morrow M P, Hutnick N A, Obeng-Adjei N, Yan J, Khan A S, Yang M, Brown A S, Wille-Reece U, Birkett A, Sardesai N Y, Zavala F and Weiner D B

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• Pneumococcal infections and vaccination

  Birgitta Henriques-Normark

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• Heat shock protein complex vaccines against mucosal pathogenic bacteria

  Phil Sutton, Jia-Xi Han, Yok Teng Chionh, Paola Cecchini and Camilo Colaco

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• Upgrading the 100 year-old BCG vaccine

  Zakaria Hmama

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• Immunization with neuraminidase deficient influenza virus is highly immunogenic and non-pathogenic to wild type and immunocompromised mice

  Alexandre Vieira Machado, Barbosa R P A, Salgado A P C, Garcia C C, Lima F H, Lopes G A O, Rachid M A5, Peixoto A C, De Oliveira D B, Ataide M C, Zirke CA, Cotrim T A, Costa E A, Almeida G M F, Russo R C and Gazzinelli R T

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• Design and evaluation of a novel OspA-based vaccine for the prevention of Lyme borreliosis

  Andreas Meinke

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• Therapeutic vaccines for drug-resistant tuberculosis

  Tjip Van Der Werf

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• Vaccination in risk groups with special focus on non-responsiveness to routine vaccines

  Ursula Wiedermann

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• Post challenging effects of new formulation of leishmania major antigen in Balb/c mice

  Latifynia Afshineh and Gharagozlou M J

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• Immunological studies on tetanus toxoid

  Rakesh Kumar

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• Process development and immunogenicity studies on a serogroup ?X? meningococcal polysaccharide conjugate vaccine

  Srinivas Reddy

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• Self-adjuvanting promiscuous peptide of Mycobacterium tuberculosis augments polyfunctional Th17 cells and evokes better memory T cell response than BCG

  Javed N Agrewala, Pradeep K Rai, Sathibabu Chodisetti, Sudeep Maurya, Sajid Nadeem, Weiguang Zeng, Ashok K Janmeja and David C Jackson

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• Immunogenicity and therapeutic effects of Ag85A/B chimeric DNA vaccine in mice infected with Mycobacterium tuberculosis

  Xueqiong Wu, Yan Liang, Junxian Zhang, Li Xiao, Yourong Yang, Xuejuan Bai, Qi Yu, Zhongming Li and Ning Li

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• Speciation of chromium in medicinal plants from selected farms in the vicinity of ferrochrome

  Isiaka Alade Owolabi, Mandiwana K L and Panichev N

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• From viruses to tumor associated antigen cancer vaccines

  Giulio Tarro

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• Measles virus vaccine infects tumor cells and induces dendritic cells (DC) maturation and tumor antigen cross-presentation

  Marc Gregoire, Guillerme Jean-Baptiste, Boisgerault Nicolas, Roulois David, Tangy Frederic and Fonteneau Jean-Fran?ois

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• Personalized therapeutic cancer vaccine development to treat metastatic diseases

  Periasamy Selvaraj

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• Teaching self-destructing Salmonella new tricks to fight cancer

  Wei Kong, Matthew Brovold, Jeffery Tully, Lee Benson, Chelsea Warren and Roy Curtiss III

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• DC targeting skin vaccines for improved cancer immunotherapy

  Yvette van Kooyk

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• Acceptability of human papillomavirus vaccine: A survey among master of business administration students in KwaZulu-Natal, South Africa

  M E Hoque and G van Hal

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• Antigenicity, structure and immunogenicity of the HIV-1 trimeric envelope glycoprotein spike

  Richard T Wyatt

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• Application of neutralization fingerprints in delineating antibody recognition in HIV-1 sera and antibody epitope prediction

  Gwo-Yu Chuang

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• The balance of cellular and humoral immunity determines the level of protection offered by a HIV vaccine in macaque models of HIV infection

  Timothy Fouts

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• VAC-3S vaccine, a novel approach to the therapeutic management of HIV infection. Overview of phase I and phase II clinical vaccine development programs

  Raphael Ho Tsong Fang, O Launay, C Katlama, J Crouzet, B Autran, V Vieillard, P Debre and S Gharakhanian

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• Characterization of a potent and broad neutralizing antibody that specifically recognizes a pointsubstitution in the 3S motif of the HIV-1 gp41 protein

  Patrice Debre, Caroline Petitdemange, Karim Dorgham, Abla Achour, Vincent Carvez, Joel Crouzet, Gabriella Scarlatti and Vincent Vieillard

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• Glycosylation of envelope gp120 is affected by producer cell type and impacts HIV-1 recognition by virus-specific antibodies and cell infection

  Milan Raska and Jan Novak

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• DNA vaccination against drug resistance in chronic viral infections, example of HIV-1

  Maria Isaguliants, Elizaveta Starodubova, Stefan Petkov, Athinakilpel?inen, Olga Krotova, Anastasia Latanova, Oleg Latyshev and Britta Wahren

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• Evaluation of immune response in small animal models by in vivo imaging

  Petkov Stefan, Starodubova Elizaveta and Isaguliants Maria

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• Human clinical trial of SAV001 prophylactic HIV vaccine and a new strategy for the development of therapeutic HIV vaccine

  Chil Yong Kang

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• Optimizing the delivery of novel immune potentiators within vaccine drug products

  Manmohan Singh

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• Natural killer cell subsets display helper and suppressor effects in modulating host viral responses in vivo

  William J Murphy

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• Strategies of antigen retargeting for improvement of DNA vaccine performance

  Elizaveta Starodubova, Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Olga Krotova, Vadim L Karpov1 and Maria Isaguliants

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• Cellular vaccines in listeriosis: Role of the listeria antigen GAPDH

  Carmen Alvarez-Dominguez

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• Regulation of STING expression via the RIG-I dependent RNA sensing pathway

  Rongtuan Lin, Yiliu Liu, Sidi Mehdi Belgnaoui, Alexander Sze, Marie-Line Goulet and Chunfu Zheng

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• Cell engineering and antibiotic-free selection for vaccinal antigens production in E. coli: The ultimate sophistication to combine safety and productivity

  Regis Sodoyer, Charlotte Mignon, Bettina Werle, Virginie Courtois and Isabelle Peubez

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• Leishmania recombinant antigen modulates the macrophage effector functions synergizing antileishmanial effects of miltefosine to facilitate early clearance of intracellular parasites

  Sunil K Arora and Anuradha Tewari

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• Immunization and human rights

  Obradovic Zarema and Obradovic Amina

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• SigN?s clinical immunomonitoring platform for the assessment of immune responses in cohort studies and clinical trials

  Brian Abel

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• Potent cellular and humoral immunogenicity of a pre-erythrocytic viral vectored malaria vaccine in African infants and children

  Katie Ewer

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• The common computer-based influenza vaccination/epidemics surrveilance system: Challenges and opportunities for primary health care in EU countries

  Ljiljana Majnaric Trtrica

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• The development of tuberculosis subunit vaccine EAMMH and regulation of vaccine induced immune memory by rapamycin

  Bingdong Zhu

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• Immunization programme in Indonesia: Overview (focusing on Streptococcus pneumonia wholecell vaccine)

  Julitasari Sundoro

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• Unique nanofabrication of antigens and adjuvants that effectively induces protective antibody and T cell responses

  Frank J Malinoski

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• Development of a carbohydrate-based vaccine against meningococcal serogroup X infection

  Francesco Berti

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• Effect of the inclusion of ?contemporary? B. pertussis strains in the vaccine composition on temporal trends in B. pertussis population

  Tatjana Pljesa

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• Specificities of health economics in the area of vaccines evaluation

  Maarten J Postma

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• The effect of new leishmania vaccine against Th1, Th2 as well as increasing of spleen white pulp size in Balb /c mice after repeated exposure

  Latifynia Afshineh, Hajaran H, Mir Amin Mohammady, Gheflati Z and N Khansari

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• A novel approach to the development of arboviral vaccines for dengue and chikungunya virus

  Malcolm E Thomas, Katherine M Smith, Caitlin M Briggs, Carla J Spears, Michelle Quiles, Mariana Ribeiro, Amanda Piper, Dennis T Brown and Raquel Hernandez

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• Strategies toward developing a universal ExPEC vaccine capable of broad protection

  Melha Mellata

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• The vaxonella platform for oral recombinant vaccine delivery

  Rocky M Cranenburgh

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• Oral vaccine platform elicits neutralizing antibody responses to influenza

  Sean Tucker

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• A rationally designed form of the TLR5 agonist, flagellin, supports superior immunogenicity of influenza B globular head vaccines

  Langzhou Song

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• Responsibility: A ?first person ethics? for vaccination

  Fermin J Gonzalez-Melado, Maria Luisa Di Pietro and Pietro Refolo

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• Development of a truly improved whooping cough vaccine

  Marcel Thalen

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• Translational development and preclinical efficacy of a multiantigen T cell epitope: Enriched DNA vaccine against Leishmaniasis

  Christiane Juhls, Shantanabha Das, Anja Freier, Thouraya Boussoffara, Sushmita Das, Detlef Oswald, Florian O Losch, Melanie Selka, Nina Sacerdoti-Sierra, Gabriele Sch?nian, Karl-Heinz Wiesm?ller, Oliver Riede, Karin Seifert, Matthias Schroff, Charles L Jaffe, Syamal Roy, Pradeep Das, Hechmi Louzir,

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• Oral Infections in Guinea Conakry

  Sylvain Haba

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