Zimmer KP
Germany
Research Article
Safety of Modified Ultra-Rush Venom Immunotherapy in Children
Author(s): Steiß JO, Lindemann H and Zimmer KPSteiß JO, Lindemann H and Zimmer KP
Background: As many as 5% of the population in Central Europe suffer from insect venom allergy. The protective effect of conventional specific immunotherapy is quite convincing, as it is associated with a success rate up to 95%. We report our experience concerning ultra-rush dose titration in children and adolescents.
Objective: The aim of this study was to examine the safety and tolerability of a shortened insect venom immunotherapy in children.
Patients and methods: A modified version of the ultra-rush procedure was initiated for 38 bee venom and 54 wasp venom allergies in 90 patients (56 boys and 34 girls) aged 4 to 17 years. Consolidation therapy consisted of 100 μg boost injections administered after seven and 21 days while maintenance therapy was administered every four to six weeks.
Results: All patients developed local reactions under VIT, of whom 20.. View More»
DOI:
10.4172/2155-6121.1000134