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Zhonghao Liu
Zhonghao Liu
China
Publications
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Short Communication
Effects of Delayed Release Microsphere of Exenatide on Peri-Implant Bone Response of Diabetic Rats
Author(s): Wenjuan Zhou,Stefan Tangl,Fei Chi,Xilong Yue,Shutai Liu,Zhonghao Liu,Xiaohui Rausch-Fan* Wenjuan Zhou,Stefan Tangl,Fei Chi,Xilong Yue,Shutai Liu,Zhonghao Liu,Xiaohui Rausch-Fan*
Objectives: The aim of this study is to evaluate and compare the impact of delayed release microsphere of exenatide on dental implants treatment of diabetic rats. Materials and methods: 6 male Zucker Diabetic Fatty (ZDF) rats were divided into three groups: GroupA, diabetic rats with dental implants (controls). Group B, diabetic rats treated with exenatide and implants placed simultaneously. Group C, diabetic rats treated with exenatide until serum glucose at a constant level and then implants were placed. Implants with surrounding bone tissues were harvested and bone responses were assessed by histomorphometric analysis. Results: Osseointegration of all implants had proceeded, bone response to implant surface of one implant in group A was similar to that in group .. View More»
DOI: 10.4172/2161-1122.1000335