Cardiovascular Pharmacology: Open Access

Zhang S

Publications

• Research Article
  Gender Based Compositional Fluctuations in Gut Microbiota in Hypertension
  Author(s): Mushtaq N, Hussain S, Yuan L, Zhang S, Li H, Ullah S and Xu J Mushtaq N, Hussain S, Yuan L, Zhang S, Li H, Ullah S and Xu J
  
  Background: Emerging evidence suggests that human gut microbiota plays a critical role in maintaining physiological homeostasis, and gut dysbiosis is involved directly or indirectly in cardiovascular diseases including hypertension. Aim: The aim of the present study was to investigate whether there were sex-based compositional differences in gut microbiota of patients with hypertension. Methods: Fecal samples were collected from male and female hypertensive patients, and healthy individuals from Xi’an, Shaanxi province of China. Touchdown PCR and denaturing gradient gel electrophoresis (PCR-DGGE) with primers specifically targeting V3 region of 16S rRNA, and real-time quantitative PCR (qPCR) were performed to characterize all the samples. High-throughput sequencing of the V3–V4 regions was performed on Illumi.. View More»
  DOI: 10.4172/2329-6607.1000248

  Abstract PDF