Journal of Nanomedicine & Nanotechnology

Zeng H

Publications

• Research Article
  Development of a Refractive Index Sensor Based on the Deposition of Gold and Silver Nanowires on ITO Glass for CA15-3 Detection
  Author(s): Zeng HZeng H
  
  As a step towards the development of highly sensitive and accurate biosensors for the early detection and monitoring of breast cancer, we have developed a refractive index sensor for the detection of CA15-3 breast cancer biomarker based on the deposition of gold and silver nanowires on ITO glass. 1 cm × 1 cm ITO glass was washed and vacuum dried. Gold films were sputtered on the clean dried ITO glass using an ion sputtering machine and labelled ITO/ Au electrode. Silver nanowires solution were deposited on the ITO/Au electrode and labelled ITO/AU/AgNWs electrode. The ITO/Au/AgNWs electrode was then embedded in a 12 well-plate containing CA15-3 antibody and labelled ITO/Au/ AgNWS/CA15-3 antibody electrode, which was used to detect CA15-3 antigen. The UV absorption wavelength of the sensor was found to be within the range of 320 nm to 350 nm. The sensor has a linear response to CA.. View More»
  DOI: 10.4172/2157-7439.1000523

  Abstract PDF