Yumiko Higuchi

Publications
  • Perspective Article
    Efficacy of Dendritic Cell-Based Cancer Immunotherapy
    Author(s): Shigetaka Shimodaira, Yumiko Higuchi, Ryu Yanagisawa, Masato Okamoto and Shigeo Koido Shigetaka Shimodaira, Yumiko Higuchi, Ryu Yanagisawa, Masato Okamoto and Shigeo Koido

    Dendritic cells (DCs) have antigen-specific bioactivity against tumor-associated antigens. The acquisition of tumor immunity with DC vaccination could be determined using both tetramer analysis and interferon γ-producing clones in enzyme-linked immunosorbent spot assays. A combination of DC vaccination with low-dose metronomic therapy and chemoradiotherapy would contribute to an enhanced acquired immunity for cancer therapy. The efficacy of DC vaccination may provide a survival benefit in some patients with cancer by achieving a prolonged quality-adjusted life year. .. View More»
    DOI: 10.4172/2161-1009.1000240

    Abstract PDF