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Ying Li
Ying Li
China
Publications
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Research Article
1H NMR-based Plasma Metabolic Profiling of Dairy Cows with Type I and Type II Ketosis
Author(s): Chuang Xu, Ying Li, Cheng Xia, Hong You Zhang, Ling Wei Sun and Chu Chu Xu Chuang Xu, Ying Li, Cheng Xia, Hong You Zhang, Ling Wei Sun and Chu Chu Xu
This study identified differences in plasma metabolites among three groups of dairy cows: type I ketotic (K1), type II ketotic (K2), and healthy control cows (C). 50 cows with two or three parities were selected at 7–28 days postpartum. Cows were classified as type I ketotic (K1, 20 cows), type II ketotic (K2, 20 cows), or healthy control cows (C, 10 cows). Plasma metabolomic profiles were analyzed by 1H-nuclear magnetic resonance technology (1H NMR). The data were processed by principal component analysis and orthogonal partial least-squares discriminant analysis (OPLS-DA). Results-The results revealed that OPLS-DA was more effective at distinguishing amongst the three groups. Additionally, there were seven different metabolites between K2 and C, 19 different metabolites between K1 and C, and 24 different metabolites between K1 and K2. Therefore, the combinatio.. View More»
DOI: 10.4172/2153-2435.1000328