Cardiovascular Pharmacology: Open Access

Yamamoto E

Publications

• Mini Review
  Potential of Monocyte Count for the Assessment of Cardiovascular Disease
  Author(s): Matsumura T*, Yamamoto E, Tsujita K and Araki E Matsumura T*, Yamamoto E, Tsujita K and Araki E
  
  Atherosclerosis is a chronic inflammatory disease proceeding from an imbalance in lipid metabolism and immune responses. Since leukocytes, especially monocytes and monocyte-derived macrophages, play pivotal roles in the progression of atherosclerosis, it is possible that monocyte count is a beneficial marker for predicting Cardiovascular Disease (CVD). Many epidemiologic and clinical studies have indicated monocytosis to be an independent predictor of cardiovascular events, both in healthy individuals at baseline and in patients with CVD or with high risk diseases for CVD, such as diabetes, dyslipidemia, hypertension and chronic kidney disease. This relationship has been observed in prospective and retrospective cohort studies, and endures after adjustment for several CVD risk factors. Other indicators utilized monocyte count, such as lymphocyte-to-monocyte ratio, monocyte-to-lymphocy.. View More»
  DOI: 10.4172/2329-6607.1000217

  Abstract PDF