Journal of Bacteriology & Parasitology

Xuefeng Chen

Publications

• Review Article
  Quorum Sensing in Vibrio and its Relevance to Bacterial Virulence
  Author(s): Huan Liu, Swaminath Srinivas, Xiaoxian He, Guoli Gong, Chunji Dai, Youjun Feng, Xuefeng Chen and Shihua WangHuan Liu, Swaminath Srinivas, Xiaoxian He, Guoli Gong, Chunji Dai, Youjun Feng, Xuefeng Chen and Shihua Wang
  
  Quorum sensing is a widespread system of cell to cell communication in bacteria that is stimulated in response to population density and relies on hormone-like chemical molecules to control gene expression. In mutualistic marine organisms like Vibrio, this system enables them to express certain processes, like virulence, only when its impact as a group would be maximized. An N-acylhomoserine lactone-dependent LuxI/R quorum sensing system has first been exemplified in Vibrio fischeri in the 1970s, regulating core bioluminescence genes. Since then, quorum sensing in Vibrio has been shown to influence a wide variety of process ranging from virulence factor formation to sporulation and motility. Most quorum sensing pathways produce and detect an autoinducer in a population dependent manner and transmit this information via a phospho-relay system to a core regulator that controls gene expr.. View More»
  DOI: 10.4172/2155-9597.1000172

  Abstract PDF