Xia Ma
IR Iran
Research Article
The Humoral and Cellular Immune Response Characteristic of Propolis
Flavonoid Used as Adjuvant to Inactivated PPV Vaccine in Sows
Author(s): Xia Ma, Zhenhuan Guo, Yonglu Liu, Yanzhou Zhou, Xiaolin Wang, Zhiqiang Shen and Jinliang Wang
Xia Ma, Zhenhuan Guo, Yonglu Liu, Yanzhou Zhou, Xiaolin Wang, Zhiqiang Shen and Jinliang Wang
The present study was conducted to assess the effects of propolis flavonoid used as adjuvant on the immune response of Landrace-Yorkshire hybrid sows immunized with an inactivated vaccine of porcine parvovirus (PPV). Thirty Landrace-Yorkshire hybrid sows were randomly assigned to one of 3 groups, and the sows in two adjuvant groups were intramuscular injected PPV vaccine with 2.0 mL propolis flavonoid adjuvant (PA) or oilemulsion adjuvant (OA), respectively. After that, serum hemagglutination inhibition antibody titers, specific IgM, IgA and IgG subclasses were measured to estimate the humoral immunity for the adjuvant effects of propolis flavonoid, as well as peripheral lymphopoiesis activity, and lymphocyte factor concentrations of Th1 and Th2 for cellular immune responses. Results indicated in a significant enhancing effect of PA on concentrations of IgM, IgG2, IgG3, IL-2 and IFN-&.. View More»
DOI:
10.4172/2161-1009.1000242