Journal of Carcinogenesis & Mutagenesis

Wolfgang Kopp

Publications

• Review Article
  Significant Dietary Changes during Human Evolution and the Development of Cancer: From Cells in Trouble to Cells Causing Trouble
  Author(s): Wolfgang Kopp Wolfgang Kopp
  
  In all western societies, mortality rates from cancer are high and even increasing. In striking contrast, cancer rates are very rare and even non-existent in primitive cultures, like hunter-gatherer (HG) populations. HGs are free of disease as long as they adhere to their traditional low-insulinemic “Paleolithic” nutrition. With acculturation and transition to current high-carbohydrate/high-insulinemic “Western” diets (HCHIDs), cancer develops in high rates. This paper follows the question of how significant nutritional changes, brought about by the Agricultural revolution, may cause development of cancer. The evidence presented shows that the switch from a Paleolithic to a Western nutrition has brought about significant metabolic perturbations, like an abnormally increased activation of the insulin-like growth factor system, the sympathetic nervous system and .. View More»
  DOI: 10.4172/2157-2518.1000303

  Abstract PDF