Walaa Fikry Mohammed Elbossaty
Damietta, Box 34517
Egypt
Research Article
Lactate Dehydrogenase (LDH) as Prognostic Marker in Acute Leukemia Quantitative Method
Author(s): Walaa Fikry Mohammed ElbossatyWalaa Fikry Mohammed Elbossaty
Lactate dehydrogenase enzyme was found in animal and human and play important role in gluconeogenesis process. It distributed in all organs, but the mainly distributed in liver. To evaluated the level of lactate dehydrogenase (LDH) in acute leukemia and investigated its clinical significance with other hematological and clinical parameters. Serum lactate dehydrogenase (LDH) level was investigated in 50 patients with acute leukemia, 17 patients with acute lymphoblastic leukemia and 33 patients with acute myeloid leukemia, in addition to 20 healthy control cases. The relationship between lactate dehydrogenase level and blood cells were analyzed. LDH level was significant elevated in acute leukemia cases as compared to control group, also LDH level was statistically significant increase in acute lymphoblastic leukemia than in acute myeloid leukemia (p<0.001). There were positively cor.. View More»
DOI:
10.4172/2155-9864.1000375