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Vipan Gupta
Vipan Gupta
India
Publications
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Research Article
Efficacy of Montelukast and Levocetirizine as Treatment for Allergic Rhinitis
Author(s): Vipan Gupta and Prithpal Singh Matreja Vipan Gupta and Prithpal Singh Matreja
Antihistamines are effective in reducing majority of symptoms of allergic rhinitis, but are ineffective for nasal congestion and nighttime symptoms. Montelukast have been found to provide quick relief. Comparison of Montelukast has been done with Antihistamines but data is limited. Hence, this study was done to compare the effectiveness of montelukast combined with levocetirizine once daily to levocetirizine alone for a 6-week treatment course of allergic rhinitis. In this randomized, open, parallel study, out of 102 patients were randomly assigned to receive montelukast and levocetirizine (treatment group) or levocetirizine alone (control group), 95 patients completed the entire 6 weeks of study. The primary outcome measure was the mean change of the total daytime nasal symptom score (PDTS) and secondary outcome measures were mean change of night time nasal, daytime eye and composite.. View More»
DOI: 10.4172/2155-6121.1000103