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Venkatachalam P
Venkatachalam P
Periyar Palkalai Nagar, Salem-636011, Tamil Nadu
India
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Research Article
Synthesis of Bioactive Chemicals Cross-linked Sodium Tripolyphosphate (TPP) - Chitosan Nanoparticles for Enhanced Cytotoxic Activity against Human Ovarian Cancer cell Line (PA-1)
Author(s): Sujima Anbu A, Sahi SV and Venkatachalam PSujima Anbu A, Sahi SV and Venkatachalam P
Currently, nanotechnology makes an impact in all spheres of human life and creates increasing excitement especially in the field of biomedicine and bionanotechnology. The important symbiosis between nanotechnology and green chemistry is the use of bioactive chemicals for the synthesis of nanoparticles. The present research was focused on fabrication of biomolecules loaded chitosan nanoparticles using Gymnema sylvestre leaf extract (GSCNPs). The experiment was performed using ionic gelation technique and was characterized using FTIR, TEM, XRD, Zeta potential and pdi. The morphological investigation showed the presence of smooth spherical surfaced GSCNPs with 58-80 nm in size. The XRD results indicated the crystalline nature of the synthesized nanoparticles. The FTIR results showed the absorption peaks stretching from higher wavelength region to lower region demonstrating the interactio.. View More»
DOI: 10.4172/2157-7439.1000418