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Uzma Azam
Uzma Azam
School of Sciences,
London
United Kingdom
Publications
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Research Article
Investigation of Interaction of Soft Nanoparticles based Vesicles with Lung Surfactant via Langmuir-Blodgett Trough and Quartz Crystal Microbalance Study
Author(s): Uzma AzamUzma Azam
Major aim of this research study is to comprehend the interaction of soft nanoparticle-based vesicles with model lung surfactant monolayer. Vertebrate lung surfactant plays a pivotal role in gaseous exchange plus breathing. As pulmonary lung surfactant is the one which directly comes in contact to inhaled air so it also acts as defensive agent against air-borne pollutants (any foreign particle). In this enquiry, several different types of lipids namely 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, 1,2-Dimitrystoyl-sn-glycero-3-phosphorylcholine, 1-palmitoyl-2-oleoyl-sn-glyceero-3-phosphocholine are used as lipid monolayer and vesicles in different combinations while using Langmuir-Blodgett trough. The different lipids are treated with chloroform and buffer solution to make vesicles and then extruded. Nanoparticles present in vesicles interact with lipid mon.. View More»
DOI: 10.4172/2157-7439.1000504