Usha Anand
India
Research Article
A Study of Plasma D-Dimer Levels in Various Stages of Liver Disease
Author(s): Dhanunjaya Y, Usha Anand and Anand CV
Dhanunjaya Y, Usha Anand and Anand CV
Aim: Defects in the process of coagulation and fibrinolysis is a common feature of various types of liver disease. The present study sought to evaluate the utility of D Dimer, a stable product of fibrinolysis in assessing this aspect of liver function. In the present study we estimated the D-Dimer levels to determine the status of coagulation defect and bleeding tendency.
Materials and methods: Ninety-nine patients with chronic liver disease were classified into groups A, B and C based upon the Child-Pugh scores. This score was calculated based upon values of serum bilirubin, serum albumin, internationalized normal ratio (INR), as well the severity of ascitis and hepatic encephalopathy. Plasma D-Dimer was estimated using an immuno-turbidimetry. The results were analyzed using the student’s ‘t’ test as well as ANOVA.
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DOI:
10.4172/2167-0889.1000119