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Toyin Jibowu
Toyin Jibowu
Faculty of Engineering, Chemical and Biochemical Engineering,
Canada
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Review Article
The Formation of Doxorubicin Loaded Targeted Nanoparticles using Nanoprecipitation, Double Emulsion and Single Emulsion for Cancer Treatment
Author(s): Toyin Jibowu Toyin Jibowu
Chemotherapeutic agents lead to the damage of healthy cells because they react with cells which are dividing at a high rate by inhibiting the DNA synthesis and interfering with the process of cell division. "Therapeutic drug delivery allows for an increase in the efficacy of the chemotherapeutic agent while minimizing the interaction with nontumour sites in the body by controlling the release rate of the therapeutic agent and having targeted sites on the nanoparticle which will allow the nanoparticle to release its contents at targeted sites." There are three main methods of creating nanocarriers for drug delivery that will be consider in this paper, nanoprecipitation, single emulsion and double emulsion. N Single emulsion is the formation of nanoparticles through oil in water emulsion. Another way to decrease the toxic effect of the drug lo.. View More»
DOI: 10.4172/2157-7439.1000379