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Toru Kono
Toru Kono
Advanced Surgery Center, 3-1, N 33, E 14, Higashi-ku, Sapporo Higashi Tokushukai Hospital,
Sapporo, Hokkaido 065-0033
Japan
Publications
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Review Article
Novel Therapeutics for Adverse Effects of Antitumor Therapy: The Promise of Multicomponent, Traditional Japanese Herbal Remedies
Author(s): Toru Kono, Hiroshi Takeda, Mitsuo Shimada, Yoshio Kase and Yasuhito UezonoToru Kono, Hiroshi Takeda, Mitsuo Shimada, Yoshio Kase and Yasuhito Uezono
In contrast to conventional single-target drugs, multi-component Kampo medicines are designed to achieve therapeutic effects through multiple drug targets. This article will discuss recent advances in mechanistic studies and the clinical effects of five representative Kampo formulations (hangeshashinto, daikenchuto, goshajinkigan, yokukansan and rikkunshito) for the treatment of adverse effects caused by anticancer drugs such as oral mucositis, diarrhea, neurotoxicity and abnormal behavior, for which western pharmaceuticals fail to adequately address. .. View More»
DOI: 10.4172/2157-2518.S8-007