Till Braunschweig
Germany
Case Report
Multiple Basaloid Follicular Hamartomas in Blaschko's Lines with and without Extracutaneous Malformations: Towards a Unifying Concept
Author(s): Marike Leijs, Till Braunschweig and Albert Rübben
Marike Leijs, Till Braunschweig and Albert Rübben
Background: Basaloid follicular hamartomas (BFHs) may occur as single isolated tumors, as localized tumors or as multiple tumors in a disseminated or in a patterned distribution. Non-hereditary multiple and mostly unilateral basaloid follicular hamartomas arranged according to Blaschko`s lines with associated extracutaneous malformations have been designated as a genetic mosaicism disease and one entity. The transition of BFH into basal cell carcinoma as well as the formation of concurrent extracutaneous malignancies has been published. Methods: We present a case of multiple and unilateral basaloid follicular hamartomas arranged according to Blaschko`s lines in multiple and anatomically separated skin areas but lacking extracutaneous malformations. Its clinical features are compared to published cases and discussed on the basis of recent findings in embryology. Results: We would propo.. View More»
DOI:
10.4172/2157-2518.S4-008