Journal of Nanomedicine & Nanotechnology

Thanapon Sangvanich

Publications

• Research Article
  Nanoporous Sorbent Material as an Oral Phosphate Binder and for Aqueous Phosphate, Chromate, and Arsenate Removal
  Author(s): Thanapon Sangvanich, Worapol Ngamcherdtrakul, Richard Lee, Jingga Morry, David Castro, Glen E Fryxell and Wassana YantaseeThanapon Sangvanich, Worapol Ngamcherdtrakul, Richard Lee, Jingga Morry, David Castro, Glen E Fryxell and Wassana Yantasee
  
  Phosphate removal is both biologically and environmentally important. Biologically, hyperphosphatemia is a critical condition in end-stage chronic kidney disease patients. Patients with hyperphosphatemia are treated long-term with oral phosphate binders to prevent phosphate absorption to the body by capturing phosphate in the gastrointestinal (GI) tract followed by fecal excretion. Environmentally, phosphate levels in natural water resources must be regulated according to limits set forth by the US Environmental Protection Agency. By utilizing nanotechnology and ligand design, we developed a new material to overcome limitations of traditional sorbent materials such as low phosphate binding capacity, slow binding kinetics, and negative interference by other anions. A phosphate binder based on ironethylenediamine on nanoporous silica (Fe-EDA-SAMMS) has been optimized for substrates and .. View More»
  DOI: 10.4172/2157-7439.1000222

  Abstract PDF