Teguh Santoso
Indonesia
Research Article
The Effects of Curcumin against the Inflammatory Response in Patients with Acute Coronary Syndrome
Author(s): Idrus Alwi, Teguh Santoso, Slamet Suyono, Bambang Sutrisna, Frans D Suyatna, Siti Boedina Kresno and Erni Purwaningsih
Idrus Alwi, Teguh Santoso, Slamet Suyono, Bambang Sutrisna, Frans D Suyatna, Siti Boedina Kresno and Erni Purwaningsih
Background: The human inflammatory response plays an important role in the pathogenesis of atherosclerosis. An increase in the inflammatory responses notable by the levels of highly sensitive C-Reactive Protein (hs-CRP) may be able to predict future cardiovascular events and the prognosis of the post-acute coronary syndrome (ACS). In animal experiments and human in-vitro experiments, curcumin has been proved to have anti-inflammatory effects. The effect of curcumin against the inflammatory response in ACS has not been identified. This study observes the effects of curcumin against the human inflammatory responses in patients with ACS. Methods: This multicenter double-blinded placebo-controlled randomized trial was located at the Intensive Coronary Care Unit (ICCU) of Cipto Mangunkusumo General Hospital, Persahabatan General Hospital and MMC Hospital in Jakarta, Indonesia. 75 ACS patie.. View More»
DOI:
10.4172/2329-6607.1000185