Surendra Singh

Surendra Singh

Tanzania

Publications
  • Research Article
    Stability of Nano Encapsulated Rice Bran Derived Bioactive Pentapeptide in Apple Juice
    Author(s): Fatima Alessa, Navam Hettiarachchy, Srinivas J Rayaprolu, Mourad Benamara, Denise Greathouse and Surendra SinghFatima Alessa, Navam Hettiarachchy, Srinivas J Rayaprolu, Mourad Benamara, Denise Greathouse and Surendra Singh

    Bioactive compounds can be derived from cereal grains and their components such as rice bran. These bioactive compounds have a potency to promote health. A pentapeptide with a sequence of amino acids Glu-Gln-Arg-Pro-Arg (EQRPR) prepared from heat stablized defatted rice bran (HDRB) has demonstrated multi-site anti-cancer properties in human cell lines. Fruit juces can be used as vehicles to incorporate the pentapeptide as a nutraceutical. To address the stability of the pentapeptide in the beverage and to prevent possible interactions with other components, nano-encapsulation with poly (lactic-co-glycolic acid) (PLGA) was used to deliver the bioactive ingredient. The nano-encapsulated pentapeptide (concentrations: 200/400/600 μg/mL) in the apple juice (model system) showed significant stability with no degradation for 2 months based on the high performance liquid chromatography a.. View More»
    DOI: 10.4172/2157-7110.1000356

    Abstract PDF