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S.S.Haque
S.S.Haque
Indira Gandhi Institute of Medical Sciences,
Patna, Bihar
India
Publications
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Research Article
Antioxidant Status of Formulated Drugs Against Typhoid
Author(s): S.S.HaqueS.S.Haque
Background: Typhoid fever (TF) is a global health problem of developing countries which is caused by Salmonella. Salmonella are facultative intra-cellular gram negative bacteria and can survive during certain stages of host parasite interaction. Most of the drugs are resistant now a days that has complicated its management, thus it has necessitated the search of formulated drugs for its treatments. Nitric oxide (NO) is a versatile molecule produced in a biological system. Previous studies have suggested that exogenous administration of L-arginine results in increased NO production, indicating that endogenous substrate is insufficient for maximal NO production. Taking these facts into consideration, it was thought pertinent to see the effect of oral administration of NO donors i.e. L-Arginine along with the low doses of antibiotic (ciprofloxacin)... View More»
DOI: 10.4172/2161-1009.1000102