Soleimany Ferizhandy Ali
Iranian blood transfusion organization-research center,
hemmat Exp way, P.O.Box: 14665-1157/Tehran
West Indies
Research Article
Platelet Activation in Stored Platelet Concentrates: Comparision of Two Methods Preparation
Author(s): Soleimany Ferizhandy Ali
Soleimany Ferizhandy Ali
Background and Objectives: This study has determined in vitro quality of 5 days stored platelet concentrates prepared by two different methods. Preparation conditions of platelet may cause platelet activation, which contributes to decreased ability of stored platelet to function. The quality platelets concentrate plays an important role in transfusion therapy. Their quality was assessed using the following parameters: platelets, leukocytes and erythrocytes counts, pH, P-selcetin (CD62P) and Annexin V.P-selectin and Annexin V can be detected on the activated platelet. Annexin V was used as a parameter for quality monitoring of platelet concentrates during storage. The present paper compares quality properties of both platelet preparations in vitro.
Methods and Materials: In this experimental study, 30 platelet concentrates prepared with plate.. View More»
DOI:
10.4172/2155-9864.1000107