Smrati Bhadauria
India
Research Article
Development of a Nanotechnology Based Biomedicine RISUG-M as a Female Contraceptive in India
Author(s): Rama Kant Singh, Falgun Wanganuji Bansode, Sharad Sharma, Poonam Singh, Smrati Bhadauria, Sarika Singh and Chandishwar Nath
Rama Kant Singh, Falgun Wanganuji Bansode, Sharad Sharma, Poonam Singh, Smrati Bhadauria, Sarika Singh and Chandishwar Nath
Background and objectives: The aim of this study was to assess the toxic effect of the newly developed contraceptive RISUG-M in female Charles Foster rats.
Methods: Young, healthy and nulliporus female rats of Charles Foster strain were employed in the study. They were randomly assigned to two groups, control and treated each consisting of female animals. The contraceptive RISUG-M was injected in the fallopian tube of the treated group rats while only vehicle was injected in control group rats’ fallopian tube and observed for a period of 14 days. Initial and final body weights and food/water consumption of the animals were recorded. The haematological and biochemical parameters were analyzed. At the end of the study all the animals were sacrificed and necropsied, the organ weight was taken and their histopathological slides were prepar.. View More»
DOI:
10.4172/2157-7439.1000297