Journal of Bioequivalence & Bioavailability

Sithara K

Publications

• Research Article
  In Silico Screening Major Spice Phytochemicals for their Novel Biological Activity and Pharmacological Fitness
  Author(s): Riju A, Sithara K, Suja S. Nair, Shamina A and Santhosh J. EapenRiju A, Sithara K, Suja S. Nair, Shamina A and Santhosh J. Eapen
  
  Spices have been known for ages as effective therap eutic food. The power of spices to impart biologica l activity is now slowly reemerging as an area of interest. We have screened 328 compounds present in five major spices namely, cinnamon ( Cinnamomum verum ), nutmeg ( Myristica fragrans ), garcinia ( Garcinia cambogia) , allspice (Pimenta dioica) and black pepper ( Piper nigrum L.) for their biological activity as promising the rapeutic com- pounds. Out of 328 compounds analyzed, ascorbic aci d, nonaldehyde, delphinidin, malabaricone-B, malaba ricone- C, isoquercitrin, quercitrin, α -bisabolol, cis-nerolidol, γ -eudesmol, hexan-1-ol and n-octanal were reported a s non- carcinogenic and non-mutagenic phytochemicals. Biol ogical activity such as antiinflammatory, antioxida nt, anti- viral (HIV), antitoxic, free radical scavenging, ca rdioprotectant, hepatoprotectant, antitu.. View More»
  DOI: 10.4172/jbb.1000010

  Abstract PDF