Simon Ayeleroun Akpona
Benin
Research Article
Nuclease Activity Associated with Secreting Granules by Lymphocytes in Patients with Bronchial Asthma
Author(s): Cyrille Alode Vodounon, Zinaida Ivanovna Abramova, Ylia Valerevna Skibo, Irina Dmitrievna Reshetnikova, Simon Ayeleroun Akpona, Haziz Sina and Lamine Baba-MoussaCyrille Alode Vodounon, Zinaida Ivanovna Abramova, Ylia Valerevna Skibo, Irina Dmitrievna Reshetnikova, Simon Ayeleroun Akpona, Haziz Sina and Lamine Baba-Moussa
Background: We know, through recent studies, the existence of some morpho-biochemical peculiarities in the process of type 1 programmed death of patients’ lymphocytes suffering from bronchial asthma, but little convincing data exist on the activity of enzymes involved in this physiological process. Therefore, the aim of our research was to study the enzymatic activity of secreting granules of patients’ lymphocytes with bronchial asthma, according to the degree of severity.
Method: The study was based on the role of granular extracts in the process of programmed death isolated lymphocytes from peripheral blood of relatively healthy individuals and asthmatic patients with different severity. The immunological characteristics of lymphocytes was done with the radial immune-diffusion method and ELISA test but the.. View More»
DOI:
10.4172/0974-8369.1000264