Shrihari TG
Krishna Devaraya College of Dental Sciences and Hospital,
Bangalore
India
Short Communication
Inflammation Related Cancer - Highlights
Author(s): Shrihari TG
Shrihari TG
Inflammation is a body response to infectious or physiological agents. During this process aggrevated chronic inflammation mediated release of various mediators such as chemokine’s, cytokines and growth factors by neutrophils, lymphocytes, and macrophages are predominant abundant cells in tumor microenvironment promotes tumor progression. Myeloid derived suppressor cells are immature myeloid progenitor cells upon activation of chronic inflammatory mediators release various factors such as COX2, INOS, ROS, Arginase1 bring about immunosuppression and tumor progression. This article highlight about inflammation related cancer mediated by macrophages and myeloid derived suppressor cells.
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DOI:
10.4172/2157-2518.1000269