Journal of Nanomedicine & Nanotechnology

Sherita L. Moses

Publications

• Research Article
  Cytotoxicity in MCF-7 and MDA-MB-231 Breast Cancer Cells, without Harming MCF-10A Healthy Cells
  Author(s): Sherita L. Moses, Edwards VM and Brantley ESherita L. Moses, Edwards VM and Brantley E
  
  Globally, breast cancer in women has become a major issue of concern, especially with treatment methods that are harmful to the patients. This research involved the trisodium citrate dihydrate (TSCD) reduction and capping of gold nanoparticles (AuNPs) to be used as a drug delivery system for Boswellia sacra (BS) and Commiphora myrrha (CM) to induce cytotoxicity in breast cancer cell lines MCF-7 and MDA-MB-231 without harming MCF-10A healthy cells. Characterization and size of nanoparticles were confirmed by UV-Visible Spectroscopy and Transmission Electron Microscopy. A pristine sample of monodispersed gold nanoparticles from 15-20 nm in size was produced. Pure plant extract was obtained and identification was confirmed using Fourier Transform Infrared Spectrometer and Gas Chromatography Mass Spectrometry. Once synthesized, two concentrations of the compou.. View More»
  DOI: 10.4172/2157-7439.1000369

  Abstract PDF